| Wed, 22 Sep 2021 | Harlescott B | 4 | 1 | Harlescott A | Won |
| Wed, 29 Sep 2021 | Wem A | 2 | 3 | Harlescott B | Won |
| Wed, 6 Oct 2021 | Harlescott B | 1 | 4 | Meole Brace F | Lost |
| Tue, 12 Oct 2021 | Unison A | 2 | 3 | Harlescott B | Won |
| Wed, 20 Oct 2021 | Harlescott B | 1 | 4 | Meole Brace A | Lost |
| Wed, 27 Oct 2021 | Beaconsfield A | 3 | 2 | Harlescott B | Lost |
| Tue, 2 Nov 2021 | Team Cup Competition | ||||
| Tue, 9 Nov 2021 | Wem C | 2 | 3 | Harlescott B | Won |
| Wed, 17 Nov 2021 | Harlescott B | 5 | 0 | Unison F | Won |
| Wed, 24 Nov 2021 | Beaconsfield B | 3 | 2 | Harlescott B | Lost |
| Wed, 1 Dec 2021 | Harlescott B | Bye 1 | |||
| Wed, 8 Dec 2021 | Bagley C | 5 | 0 | Harlescott B | Lost |
| Wed, 15 Dec 2021 | Harlescott A | 5 | 0 | Harlescott B | Lost |
| Tue, 21 Dec 2021 | Christmas/New Year | ||||
| Tue, 28 Dec 2021 | Christmas/New Year | ||||
| Wed, 5 Jan 2022 | Harlescott B | 1 | 4 | Wem A | Lost |
| Wed, 12 Jan 2022 | Meole Brace F | 5 | 0 | Harlescott B | Lost |
| Wed, 19 Jan 2022 | Harlescott B | 1 | 4 | Unison A | Lost |
| Tue, 25 Jan 2022 | League Cup Competitions | ||||
| Tue, 1 Feb 2022 | Meole Brace A | 5 | 0 | Harlescott B | Lost |
| Wed, 9 Feb 2022 | Harlescott B | 0 | 5 | Beaconsfield A | Lost |
| Wed, 16 Feb 2022 | Harlescott B | 2 | 3 | Wem C | Lost |
| Wed, 23 Feb 2022 | Unison F | 3 | 2 | Harlescott B | Lost |
| Wed, 2 Mar 2022 | Harlescott B | 1 | 4 | Beaconsfield B | Lost |
| Wed, 9 Mar 2022 | Bye 1 | Harlescott B | |||
| Wed, 16 Mar 2022 | Harlescott B | 1 | 4 | Bagley C | Lost |
| Wed, 23 Mar 2022 | League Handicap Comp @ Meole | ||||
| Wed, 30 Mar 2022 | Cup Competition Week | ||||
| Sat, 2 Apr 2022 | Finals/Presentation Night @ Unison | ||||